Genotoxic and Mutagenic Effects of Melissa officinalis (Erva Cidreira) Extracts

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Genotoxic and Mutagenic Effects of Melissa officinalis (Erva Cidreira) Extracts

Erva cidreira (Melissa officinalis) is a plant with sedative properties and in Brazil it has been used for insomnia and anxiety. It is also employed to stimulate liver functions and normalize menstruation and for intestinal constipation. The aim of this work was to evaluate the genotoxic and mutagenic effects of erva cidreira. Results indicate the presence of genotoxic activity in the lyophiliz...

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Evaluation of the genotoxic and antigenotoxic potential of Melissa officinalis in mice

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Synergistic antibacterial interaction between Melissa officinalis extracts and antibiotics

Synergism between water, ethanol and ethyl acetate extract of Melissa officinalis and five commonly used antibiotics (streptomycin, chloramphenicol, tetracycline, amoxicillin, rifamycine) were investigated by disc diffusion method in relation to antibiotic-susceptible and antibiotic resistant human-pathogenic bacteria. The total phenol content in the extracts were determined by Folin-Ciocalteau...

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Rosmarinic Acid and Melissa officinalis Extracts Differently Affect Glioblastoma Cells

Lemon balm (Melissa officinalis L.) has many biological effects but especially important is its neuroprotective activity. The aim of the study is to produce different extracts of Melissa officinalis and analyse their chemical composition and biological properties on rat glioblastoma C6 cells. Results revealed that rosmarinic acid (RA) is the predominant compound of lemon balm extracts. RA has c...

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Formulation of a Sedative Film Coated Tablet from Extracts of Melissa officinalis and Valeriana officinalis

Anxiety is feeling of danger in a person who is threatening with something. Nowadays, anxiety is increased in different populations and, thus it is became an important problem in many countries. Melissa officinalis (Melissa) and Valeriana officinalis (Valerian) are two medicinal plants. These two plants are traditionally used as sedative herbal drugs and new studies on their pharmacological act...

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ژورنال

عنوان ژورنال: The Open Toxicology Journal

سال: 2009

ISSN: 1874-3404

DOI: 10.2174/1874340400903010058